Aboard the wreck of the infamous Queen Anne's Revenge is a cache of medical instruments once used to keep pirates feeling seaworthy. What do they reveal about the horrors of medicine on the high seas? In the ancient fortress of Kuelap, Peru, archaeologists uncover human remains bearing strange surgical markings. What mysterious ailments were Andean healers attempting to treat? And what sophisticated anatomical knowledge must they have possessed to resort to ancient surgery? As Lewis and Clark embark on their fabled expedition, they carry an unusual medical arsenal that includes 'thunderbolts.' Remnants of this potent purgative have been unearthed in expedition latrines.